structure

We use X-ray crystallography and electron microscopy to analyze the structure and function of proteins and other macromolecules. 

Click on the image to download the PDB file:

Cytoplasmic domain of the Thermomonospora curvata Type VII Secretion ATPase EccC

Thermomonospora curvata Type VII Secretion ATPase EccC (ATPase 2 and 3) bound to the EsxB signal sequence

Crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing

Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi

Geobacillus sp. EccC (ATPase 2 and 3)

Thermomonospora curvata Type VII Secretion substrates EsxA and EsxB in complex

EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins.

Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.

Structure of the Auto-inhibited Kinase Domain of CaMKII and SAXS Analysis of the Holoenzyme

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Graduate Students

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Post-Doctoral Researchers

Preference will be given to those with a background in structural biology or bacterial pathogenesis.

E-mail a CV and cover letter to oren.rosenberg [at sign] ucsf.edu. Please describe your background experience; what about the lab interests you and your career goals.